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Expansion of hematopoietic stem cells from normal donors and bone marrow failure patients by recombinant hoxb4
We produced six versions of recombinant human hoxb4 proteins and evaluated their effectiveness in expanding human hematopoietic stem and progenitor cells in vitro and in vivo. An N-terminal-tat and C-terminal histidine-tagged version of hoxb4 (T-hoxb4-H) had the highest activity in expanding colony...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666942/ https://ncbi.nlm.nih.gov/pubmed/19120358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2008.07509.x |
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