An Evaluation of μ-Opioid Receptor (OPRM1) as a Predictor of Naltrexone Response in the Treatment of Alcohol Dependence: Results From the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) Study

CONTEXT: Naltrexone hydrochloride treatment for alcohol dependence works for some individuals but not for everyone. Asn40Asp, a functional polymorphism of the μ-opioid receptor gene (OPRM1), might predict naltrexone response. OBJECTIVE: To evaluate whether individuals with alcoholism who are heteroz...

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Päätekijät: Anton, Raymond F., Oroszi, Gabor, O'Malley, Stephanie, Couper, David, Swift, Robert, Pettinati, Helen, Goldman, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666924/
https://ncbi.nlm.nih.gov/pubmed/18250251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archpsyc.65.2.135
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