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An analysis of the effect of mu-opioid receptor gene (OPRM1) promoter region DNA methylation on the response of naltrexone treatment of alcohol dependence

This study explored the effect of OPRM1 promoter region DNA methylation on the outcome of treatment with the opioid antagonist naltrexone (NTX) for alcohol dependence (AD). Ninety-three patients with DSM-IV AD [41 African Americans (AAs) and 52 European Americans (EAs)] received double-blind treatme...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics J
Main Authors: Lin, Yufei, Kranzler, Henry R., Farrer, Lindsay A., Xu, Hongqin, Henderson, David C., Zhang, Huiping
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415483/
https://ncbi.nlm.nih.gov/pubmed/32029903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41397-020-0158-1
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