Systematic Review and Meta-Analysis of the Moderating Effect of rs1799971 in OPRM1, the Mu-opioid Receptor Gene, on Response to Naltrexone Treatment of Alcohol Use Disorder

BACKGROUND AND AIMS: There is wide inter-individual variability in response to the treatment of alcohol use disorder (AUD) with the opioid receptor antagonist naltrexone. To identify patients who may be most responsive to naltrexone treatment, studies have examined the moderating effect of rs1799971...

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Publicado en:Addiction
Main Authors: Hartwell, Emily E., Feinn, Richard, Morris, Paige E., Gelernter, Joel, Krystal, John, Arias, Albert J., Hoffman, Michaela, Petrakis, Ismene, Gueorguieva, Ralitza, Schacht, Joseph P., Oslin, David, Anton, Raymond F., Kranzler, Henry R.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340566/
https://ncbi.nlm.nih.gov/pubmed/31961981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/add.14975
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