OPRM1 Asn40Asp predicts response to naltrexone treatment; a haplotype-based approach

BACKGROUND: Individualized pharmacotherapy requires identification of genetic variants predictive of treatment response. In OPRM1, Asn40Asp has been reported to be predictive of response to naltrexone treatment. Nevertheless, the in vitro function of the polymorphism remains elusive and over 300 OPR...

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Detalhes bibliográficos
Main Authors: Oroszi, Gabor, Anton, Raymond F., O’Malley, Stephanie, Swift, Robert, Pettinati, Helen, Couper, David, Yuan, Qiaoping, Goldman, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679376/
https://ncbi.nlm.nih.gov/pubmed/19053977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2008.00846.x
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