High-salt diet enhances mouse aortic relaxation through adenosine A(2A) receptor via CYP epoxygenases

We hypothesize that A(2A) adenosine receptors (A(2A) AR) promote aortic relaxation in mice through cytochrome P450 (CYP)-epoxygenases and help to avoid salt sensitivity. Aortas from male mice maintained on a high-salt (HS; 7% NaCl) or normal-salt (NS; 0.45% NaCl) diet for 4–5 wks were used. Concentr...

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Hlavní autoři: Nayeem, Mohammed A., Ponnoth, Dovenia S., Boegehold, Matthew A., Zeldin, Darryl C., Falck, John R., Mustafa, S. Jamal
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2009
Témata:
Receptors and Signaling Pathways
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665852/
https://ncbi.nlm.nih.gov/pubmed/19109366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.90798.2008
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