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Role of CYP epoxygenases in A(2A)AR-mediated relaxation using A(2A)AR-null and wild-type mice

We hypothesized that A(2A) adenosine receptor (A(2A)AR) activation causes vasorelaxation through cytochrome P-450 (CYP) epoxygenases and endothelium-derived hyperpolarizing factors, whereas lack of A(2A)AR activation promotes vasoconstriction through Cyp4a in the mouse aorta. Adenosine 5′-N-ethylcar...

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Detalhes bibliográficos
Main Authors: Nayeem, Mohammed A., Poloyac, Samuel M., Falck, John R., Zeldin, Darryl C., Ledent, Catherine, Ponnoth, Dovenia S., Ansari, Habib R., Mustafa, S. Jamal
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614586/
https://ncbi.nlm.nih.gov/pubmed/18805895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01333.2007
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