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The Death Domain of FADD Is Essential for Embryogenesis, Lymphocyte Development, and Proliferation
The Fas-associated death domain-containing protein (FADD) is an adaptor for relaying apoptotic signals initiated by death receptors such as Fas. Whereas a lack of death receptors has no effect on mouse development, FADD deficiency results in early embryonic lethality, indicating that FADD has additi...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665115/ https://ncbi.nlm.nih.gov/pubmed/19203997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900249200 |
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