BLNK Binds Active H-Ras to Promote B Cell Receptor-mediated Capping and ERK Activation

Cross-linked B cell receptor (BCR) aggregates on the cell surface, then assembles into the “cap” where Ras is co-localized, and transduces various intracellular signals including Ras-ERK activation. BCR signals induce proliferation, differentiation, or apoptosis of B cells depending on their maturat...

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Main Authors: Imamura, Yasuhiro, Oda, Akihisa, Katahira, Takashi, Bundo, Kenji, Pike, Kelly A., Ratcliffe, Michael J. H., Kitamura, Daisuke
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665102/
https://ncbi.nlm.nih.gov/pubmed/19218240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809051200
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