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Enhanced Angiogenesis and Reduced Contraction in Thrombospondin-2–null Wounds Is Associated With Increased Levels of Matrix Metalloproteinases-2 and -9, and Soluble VEGF

Thrombospondin-2 (TSP2) is an inhibitor of angiogenesis with pro-apoptotic and anti-proliferative effects on endothelial cells. Mice deficient in this matricellular protein display improved recovery from ischemia and accelerated wound healing associated with alterations in angiogenesis and extracell...

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Bibliografiska uppgifter
Huvudupphovsmän: MacLauchlan, Susan, Skokos, Eleni A., Agah, Azin, Zeng, Jianmin, Tian, Weiming, Davidson, Jeffrey M., Bornstein, Paul, Kyriakides, Themis R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Histochemical Society 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664984/
https://ncbi.nlm.nih.gov/pubmed/19029404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/jhc.2008.952689
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