Low Enzymatic Activity Haplotypes of the Human Catechol-O-Methyltransferase Gene: Enrichment for Marker SNPs

Catechol-O-methyltransferase (COMT) is an enzyme that plays a key role in the modulation of catechol-dependent functions such as cognition, cardiovascular function, and pain processing. Three common haplotypes of the human COMT gene, divergent in two synonymous and one nonsynonymous (val (158) met)...

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Detalhes bibliográficos
Main Authors: Nackley, Andrea G., Shabalina, Svetlana A., Lambert, Jason E., Conrad, Mathew S., Gibson, Dustin G., Spiridonov, Alexey N., Satterfield, Sarah K., Diatchenko, Luda
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664927/
https://ncbi.nlm.nih.gov/pubmed/19365560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005237
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