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Tautomycin suppresses growth and neuroendocrine hormone markers in carcinoid cells through activation of the Raf-1 pathway

BACKGROUND: Carcinoids are neuroendocrine (NE) tumors with limited treatment options. Raf-1 pathway activation has been shown to suppress hormone production in carcinoid cells. Here, we investigated a novel treatment for carcinoid cell growth based on pharmacologic Raf-1 activation using the compoun...

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Detalhes bibliográficos
Main Authors: Pinchot, Scott N., Adler, Joel T., Luo, Yinggang, Ju, Jianhua, Li, Wenli, Shen, Ben, Kunnimalaiyaan, Muthusamy, Chen, Herbert
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664746/
https://ncbi.nlm.nih.gov/pubmed/19245907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjsurg.2008.10.007
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