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Resveratrol Induces Notch2-mediated Apoptosis and Suppression of Neuroendocrine Markers in Medullary Thyroid Cancer

BACKGROUND: Currently, complete surgical resection is the only curative option for MTC. Previous work has shown the Notch pathway is a potent tumor suppressor in MTC and that Resveratrol activates the Notch pathway in carcinoid cancer, a related NE malignancy. In this study, we hypothesized that the...

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Detalhes bibliográficos
Main Authors: Truong, Matthew, Cook, Mackenzie R., Pinchot, Scott N., Kunnimalaiyaan, Muthusamy, Chen, Herbert
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078954/
https://ncbi.nlm.nih.gov/pubmed/21184191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-010-1488-z
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