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Hepatitis C virus NS2 is a protease stimulated by cofactor domains in NS3

Chronic infection with hepatitis C virus (HCV) affects 130 million people worldwide and is a major cause of liver cirrhosis and liver cancer. After translation of the HCV RNA genome into a polyprotein, 2 viral proteases process its non-structural protein (NS) region. While the essential chymotrypsin...

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Bibliografiske detaljer
Main Authors: Schregel, V., Jacobi, S., Penin, F., Tautz, N.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663979/
https://ncbi.nlm.nih.gov/pubmed/19282477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810950106
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