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Transcription factor expression dynamics of early T-lymphocyte specification and commitment
Mammalian T lymphocytes are a prototype for development from adult pluripotent stem cells. While T-cell specification is driven by Notch signaling, T-lineage commitment is only finalized after prolonged Notch activation. However, no T-lineage specific regulatory factor has been reported that mediate...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663971/ https://ncbi.nlm.nih.gov/pubmed/19013443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.10.021 |
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