Transcription factor expression dynamics of early T-lymphocyte specification and commitment

Mammalian T lymphocytes are a prototype for development from adult pluripotent stem cells. While T-cell specification is driven by Notch signaling, T-lineage commitment is only finalized after prolonged Notch activation. However, no T-lineage specific regulatory factor has been reported that mediate...

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Main Authors: David-Fung, Elizabeth-Sharon, Butler, Robert, Buzi, Gentian, Yui, Mary A., Diamond, Rochelle A., Anderson, Michele K., Rowen, Lee, Rothenberg, Ellen V.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663971/
https://ncbi.nlm.nih.gov/pubmed/19013443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.10.021
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