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Multi-scale dynamical modelling of T-cell development from an early thymic progenitor state to lineage commitment
Intrathymic development of committed pro-T-cells from multipotent hematopoietic precursors offers a unique opportunity to dissect the molecular circuitry establishing cell identity in response to environmental signals. This transition encompasses programmed shutoff of stem/progenitor genes, upregula...
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| Publicado en: | Cell Rep |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7943435/ https://ncbi.nlm.nih.gov/pubmed/33440162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108622 |
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