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Identification of a T lineage committed progenitor in adult blood
With help of a hCD25 reporter controlled by Ptcra regulatory elements T cell precursors were identified in peripheral blood. Sca-1(+), IL-7Rα(+), Flt3(−) precursors that were c-kit(lo) and Thy-1(hi) generated T lineage cells when cultured on OP9-DL1 stromal cells and upon transfer into Rag(−/−)γ(c)(...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1828638/ https://ncbi.nlm.nih.gov/pubmed/17222572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2006.12.004 |
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