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Phosphoproteomic analysis of human brain by calcium phosphate precipitation and mass spectrometry
Alzheimer’s disease (AD), the most common form of dementia, is manifested in the brain by the aggregation of amyloid plaques and neurofibrillary tangles. The tangles are primarily composed of microtubule-associated protein tau that is aberrantly hyperphosphorylated, suggesting that deregulated phosp...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663965/ https://ncbi.nlm.nih.gov/pubmed/18510355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr8000496 |
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