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Quantitative Phosphoproteomics of Alzheimer's Disease Reveals Crosstalk between Kinases and Small Heat Shock Proteins

Abnormal phosphorylation contributes to the formation of neurofibrillary tangles in Alzheimer Disease (AD), but may play other signaling roles during AD pathogenesis. In this study, we employed immobilized metal affinity chromatography (IMAC) followed by liquid chromatography-tandem mass spectrometr...

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Detalhes bibliográficos
Publicado no:Proteomics
Main Authors: Dammer, Eric B., Lee, Andrew K., Duong, Duc M., Gearing, Marla, Lah, James J., Levey, Allan I., Seyfried, Nicholas T
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404162/
https://ncbi.nlm.nih.gov/pubmed/25332170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400189
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