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Quantitative Phosphoproteomics of Alzheimer's Disease Reveals Crosstalk between Kinases and Small Heat Shock Proteins
Abnormal phosphorylation contributes to the formation of neurofibrillary tangles in Alzheimer Disease (AD), but may play other signaling roles during AD pathogenesis. In this study, we employed immobilized metal affinity chromatography (IMAC) followed by liquid chromatography-tandem mass spectrometr...
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| Опубликовано в: : | Proteomics |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4404162/ https://ncbi.nlm.nih.gov/pubmed/25332170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400189 |
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