Quantitative Phosphoproteomics of Alzheimer's Disease Reveals Crosstalk between Kinases and Small Heat Shock Proteins

Abnormal phosphorylation contributes to the formation of neurofibrillary tangles in Alzheimer Disease (AD), but may play other signaling roles during AD pathogenesis. In this study, we employed immobilized metal affinity chromatography (IMAC) followed by liquid chromatography-tandem mass spectrometr...

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Detalles Bibliográficos
Publicado en:Proteomics
Main Authors: Dammer, Eric B., Lee, Andrew K., Duong, Duc M., Gearing, Marla, Lah, James J., Levey, Allan I., Seyfried, Nicholas T
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404162/
https://ncbi.nlm.nih.gov/pubmed/25332170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400189
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