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USP9X Enhances the Polarity and Self-Renewal of Embryonic Stem Cell-derived Neural Progenitors

The substrate-specific deubiquitylating enzyme USP9X is a putative “stemness” gene expressed in many progenitor cell populations. To test its function in embryonic stem cell-derived neural progenitor/stem cells, we expressed USP9X from a Nestin promoter. Elevated USP9X levels resulted in two phenome...

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Hlavní autoři: Jolly, Lachlan A., Taylor, Verdon, Wood, Stephen A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663926/
https://ncbi.nlm.nih.gov/pubmed/19176755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0596
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