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Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors

Development of neural progenitors depends upon the coordination of appropriate intrinsic responses to extrinsic signalling pathways. Here we show the deubiquitylating enzyme, Usp9x regulates components of both intrinsic and extrinsic fate determinants. Nestin-cre mediated ablation of Usp9x from embr...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Premarathne, Susitha, Murtaza, Mariyam, Matigian, Nicholas, Jolly, Lachlan A., Wood, Stephen A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556043/
https://ncbi.nlm.nih.gov/pubmed/28808228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05451-5
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