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Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors

Development of neural progenitors depends upon the coordination of appropriate intrinsic responses to extrinsic signalling pathways. Here we show the deubiquitylating enzyme, Usp9x regulates components of both intrinsic and extrinsic fate determinants. Nestin-cre mediated ablation of Usp9x from embr...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Premarathne, Susitha, Murtaza, Mariyam, Matigian, Nicholas, Jolly, Lachlan A., Wood, Stephen A.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556043/
https://ncbi.nlm.nih.gov/pubmed/28808228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05451-5
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