USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitors

USP9X, is highly expressed in neural progenitors and, essential for neural development in mice. In humans, mutations in USP9X are associated with neurodevelopmental disorders. To understand USP9X’s role in neural progenitors, we studied the effects of altering its expression in both the human neural...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bridges, Caitlin R., Tan, Men-Chee, Premarathne, Susitha, Nanayakkara, Devathri, Bellette, Bernadette, Zencak, Dusan, Domingo, Deepti, Gecz, Jozef, Murtaza, Mariyam, Jolly, Lachlan A., Wood, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427856/
https://ncbi.nlm.nih.gov/pubmed/28341829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00149-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados