Physicochemical Characterization of Efavirenz–Cyclodextrin Inclusion Complexes

Efavirenz (EFV) is an oral antihuman immunodeficiency virus type 1 drug with extremely poor aqueous solubility. Thus, its gastrointestinal absorption is limited by the dissolution rate of the drug. The objective of this study was to characterize the inclusion complexes of EFV with β-cyclodextrin (β-...

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Autors principals: Sathigari, Sateeshkumar, Chadha, Gurkishan, Lee, Y-H. Phillip, Wright, Nydeia, Parsons, Daniel L., Rangari, Vijay K., Fasina, Oladiran, Babu, R. Jayachandra
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663670/
https://ncbi.nlm.nih.gov/pubmed/19148759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9180-3
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