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Physicochemical Characterization of Efavirenz–Cyclodextrin Inclusion Complexes

Efavirenz (EFV) is an oral antihuman immunodeficiency virus type 1 drug with extremely poor aqueous solubility. Thus, its gastrointestinal absorption is limited by the dissolution rate of the drug. The objective of this study was to characterize the inclusion complexes of EFV with β-cyclodextrin (β-...

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Hlavní autoři: Sathigari, Sateeshkumar, Chadha, Gurkishan, Lee, Y-H. Phillip, Wright, Nydeia, Parsons, Daniel L., Rangari, Vijay K., Fasina, Oladiran, Babu, R. Jayachandra
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663670/
https://ncbi.nlm.nih.gov/pubmed/19148759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9180-3
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