Physicochemical Characterization of Efavirenz–Cyclodextrin Inclusion Complexes

Efavirenz (EFV) is an oral antihuman immunodeficiency virus type 1 drug with extremely poor aqueous solubility. Thus, its gastrointestinal absorption is limited by the dissolution rate of the drug. The objective of this study was to characterize the inclusion complexes of EFV with β-cyclodextrin (β-...

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Detalhes bibliográficos
Main Authors: Sathigari, Sateeshkumar, Chadha, Gurkishan, Lee, Y-H. Phillip, Wright, Nydeia, Parsons, Daniel L., Rangari, Vijay K., Fasina, Oladiran, Babu, R. Jayachandra
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663670/
https://ncbi.nlm.nih.gov/pubmed/19148759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9180-3
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