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Oxidative Stress, Mitochondria and mtDNA-mutator Mice
The oxidative stress theory of aging, an expansion of the mitochondrial theory of aging, is based around the idea of a vicious cycle, in which somatic mutations of mitochondrial DNA (mtDNA) provoke respiratory chain dysfunction leading to enhanced ROS production and in turn to the accumulation of fu...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663522/ https://ncbi.nlm.nih.gov/pubmed/17126516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2006.10.018 |
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