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Oxidative Stress, Mitochondria and mtDNA-mutator Mice

The oxidative stress theory of aging, an expansion of the mitochondrial theory of aging, is based around the idea of a vicious cycle, in which somatic mutations of mitochondrial DNA (mtDNA) provoke respiratory chain dysfunction leading to enhanced ROS production and in turn to the accumulation of fu...

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Bibliografische gegevens
Hoofdauteur: Thompson, LaDora V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663522/
https://ncbi.nlm.nih.gov/pubmed/17126516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2006.10.018
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