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The Region Approximately between Amino Acids 81 and 137 of Proteinase K-Resistant PrP(Sc) Is Critical for the Infectivity of the Chandler Prion Strain
Although the major component of the prion is believed to be the oligomer of PrP(Sc), little information is available concerning regions on the PrP(Sc) molecule that affect prion infectivity. During the analysis of PrP(Sc) molecules from various prion strains, we found that PrP(Sc) of the Chandler st...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663276/ https://ncbi.nlm.nih.gov/pubmed/19176630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01740-08 |
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