In Vivo gp41 Antibodies Targeting the 2F5 Monoclonal Antibody Epitope Mediate Human Immunodeficiency Virus Type 1 Neutralization Breadth

The broadly neutralizing human monoclonal antibodies (MAbs) 2F5 and 4E10, both targeting the highly conserved human immunodeficiency virus type 1 (HIV-1) envelope membrane proximal external region (MPER), are among the MAbs with the broadest heterologous neutralizing activity and are of considerable...

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Detalhes bibliográficos
Main Authors: Shen, Xiaoying, Parks, Robert J., Montefiori, David C., Kirchherr, Jennifer L., Keele, Brandon F., Decker, Julie M., Blattner, William A., Gao, Feng, Weinhold, Kent J., Hicks, Charles B., Greenberg, Michael L., Hahn, Beatrice H., Shaw, George M., Haynes, Barton F., Tomaras, Georgia D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663270/
https://ncbi.nlm.nih.gov/pubmed/19193787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02631-08
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