In Vivo gp41 Antibodies Targeting the 2F5 Monoclonal Antibody Epitope Mediate Human Immunodeficiency Virus Type 1 Neutralization Breadth

The broadly neutralizing human monoclonal antibodies (MAbs) 2F5 and 4E10, both targeting the highly conserved human immunodeficiency virus type 1 (HIV-1) envelope membrane proximal external region (MPER), are among the MAbs with the broadest heterologous neutralizing activity and are of considerable...

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Bibliografiske detaljer
Main Authors: Shen, Xiaoying, Parks, Robert J., Montefiori, David C., Kirchherr, Jennifer L., Keele, Brandon F., Decker, Julie M., Blattner, William A., Gao, Feng, Weinhold, Kent J., Hicks, Charles B., Greenberg, Michael L., Hahn, Beatrice H., Shaw, George M., Haynes, Barton F., Tomaras, Georgia D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663270/
https://ncbi.nlm.nih.gov/pubmed/19193787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02631-08
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