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Human Respiratory Syncytial Virus Nonstructural Protein NS2 Antagonizes the Activation of Beta Interferon Transcription by Interacting with RIG-I

A wide variety of RNA viruses have been shown to produce proteins that inhibit interferon (IFN) production and signaling. For human respiratory syncytial virus (RSV), the nonstructural NS1 and NS2 proteins have been shown to block IFN signaling by causing the proteasomal degradation of STAT2. In add...

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Détails bibliographiques
Auteurs principaux: Ling, Zhenhua, Tran, Kim C., Teng, Michael N.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663251/
https://ncbi.nlm.nih.gov/pubmed/19193793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02434-08
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