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Double-Stranded RNA Binding of Influenza B Virus Nonstructural NS1 Protein Inhibits Protein Kinase R but Is Not Essential To Antagonize Production of Alpha/Beta Interferon

Expression of alpha/beta interferon (IFN-α/β) in virus-infected vertebrate cells is a key event in the establishment of a sustained antiviral response, which is triggered by double-stranded RNA (dsRNA) produced during viral replication. These antiviral cytokines initiate the expression of cellular p...

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Detalhes bibliográficos
Main Authors: Dauber, Bianca, Schneider, Jana, Wolff, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1642593/
https://ncbi.nlm.nih.gov/pubmed/16987984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01142-06
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