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Signal Regulatory Proteins (SIRPS) Are Secreted Presynaptic Organizing Molecules

Formation of chemical synapses requires exchange of organizing signals between the synaptic partners. Using synaptic vesicle aggregation in cultured neurons as a marker of presynaptic differentiation, we purified candidate presynaptic organizers from mouse brain. A major bioactive species was the ex...

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Detalhes bibliográficos
Main Authors: Umemori, Hisashi, Sanes, Joshua R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662226/
https://ncbi.nlm.nih.gov/pubmed/18819922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805729200
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