Metalloproteinase- and γ-Secretase-mediated Cleavage of Protein-tyrosine Phosphatase Receptor Type Z

Protein-tyrosine phosphatase receptor type Z (Ptprz) is preferentially expressed in the brain as a major chondroitin sulfate proteoglycan. Three splicing variants, two receptor isoforms and one secretory isoform, are known. Here, we show that the extracellular region of the receptor isoforms of Ptpr...

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Hlavní autoři: Chow, Jeremy Pak Hong, Fujikawa, Akihiro, Shimizu, Hidetada, Suzuki, Ryoko, Noda, Masaharu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662165/
https://ncbi.nlm.nih.gov/pubmed/18713734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802976200
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