A carregar...
In Vivo Analysis of Protein Kinase B (PKB)/Akt Regulation in DNA-PKcs-null Mice Reveals a Role for PKB/Akt in DNA Damage Response and Tumorigenesis
Full activation of protein kinase B (PKB/Akt) requires phosphorylation on Thr-308 and Ser-473. It is well established that Thr-308 is phosphorylated by 3-phosphoinositide-dependent kinase-1 (PDK1). Ser-473 phosphorylation is mediated by both mammalian target of rapamycin-rictor complex (mTORC2) and...
Na minha lista:
Main Authors: | , , , , |
---|---|
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
|
Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662067/ https://ncbi.nlm.nih.gov/pubmed/18757368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803053200 |
Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|