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Deletion of PKBα/Akt1 Affects Thymic Development
BACKGROUND: The thymus constitutes the primary lymphoid organ for the majority of T cells. The phosphatidyl-inositol 3 kinase (PI3K) signaling pathway is involved in lymphoid development. Defects in single components of this pathway prevent thymocytes from progressing beyond early T cell development...
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Main Authors: | , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Public Library of Science
2007
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1991598/ https://ncbi.nlm.nih.gov/pubmed/17912369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000992 |
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