Deletion of PKBα/Akt1 Affects Thymic Development

BACKGROUND: The thymus constitutes the primary lymphoid organ for the majority of T cells. The phosphatidyl-inositol 3 kinase (PI3K) signaling pathway is involved in lymphoid development. Defects in single components of this pathway prevent thymocytes from progressing beyond early T cell development...

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Autori principali: Fayard, Elisabeth, Gill, Jason, Paolino, Magdalena, Hynx, Debby, Holländer, Georg A., Hemmings, Brian A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991598/
https://ncbi.nlm.nih.gov/pubmed/17912369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000992
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