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Loss of PKBβ/Akt2 predisposes mice to ovarian cyst formation and increases the severity of polycystic ovary formation in vivo

Ovarian cysts affect women of all ages and decrease fertility. In particular, polycystic ovarian syndrome (PCOS), in which multiple follicular cysts develop, affects 5–10% of women of reproductive age and can result in infertility. Current non-invasive treatments for PCOS can resolve cysts and resto...

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Detalhes bibliográficos
Main Authors: Restuccia, David F., Hynx, Debby, Hemmings, Brian A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339834/
https://ncbi.nlm.nih.gov/pubmed/22275470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.008136
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