Human IgG2 Antibody Disulfide Rearrangement in Vivo

Proteins destined to circulate in the blood are first folded and assembled in the endoplasmic reticulum of secretory cells. For antibodies, like many other serum proteins, the folding and assembly steps involve the formation of disulfide bonds. Such bonds have been thought to be static features of p...

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Bibliografiske detaljer
Main Authors: Liu, Y. Diana, Chen, Xiaoyu, Enk, Jian Zhang-van, Plant, Matt, Dillon, Thomas M., Flynn, Gregory C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662016/
https://ncbi.nlm.nih.gov/pubmed/18713741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804787200
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