Human IgG2 Antibodies Display Disulfide-mediated Structural Isoforms

In this work, we present studies of the covalent structure of human IgG2 molecules. Detailed analysis showed that recombinant human IgG2 monoclonal antibody could be partially resolved into structurally distinct forms caused by multiple disulfide bond structures. In addition to the presently accepte...

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Detaylı Bibliyografya
Asıl Yazarlar: Wypych, Jette, Li, Ming, Guo, Amy, Zhang, Zhongqi, Martinez, Theresa, Allen, Martin J., Fodor, Szilan, Kelner, Drew N., Flynn, Gregory C., Liu, Yaoqing Diana, Bondarenko, Pavel V., Ricci, Margaret Speed, Dillon, Thomas M., Balland, Alain
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2008
Konular:
Protein Structure and Folding
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259661/
https://ncbi.nlm.nih.gov/pubmed/18339624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709987200
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