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Protected hinge in the immunoglobulin G2-A(2) disulfide isoform
Human IgG2 consists of disulfide-mediated structural isoforms, classified by the number of Fab arms disulfide-linked to the heavy chain hinge. In the IgG2-B isoform, both Fab arms are linked to the hinge region, and in IgG2-A, neither Fab arm are linked to the hinge. IgG2-A/B is a hybrid between the...
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| Udgivet i: | Protein Sci |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4253815/ https://ncbi.nlm.nih.gov/pubmed/25264323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2557 |
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