MERIT40 controls BRCA1–Rap80 complex integrity and recruitment to DNA double-strand breaks

Rap80 targets the breast cancer suppressor protein BRCA1 along with Abraxas and the BRCC36 deubiquitinating enzyme (DUB) to polyubiquitin structures at DNA double-strand breaks (DSBs). These DSB targeting events are essential for BRCA1-dependent DNA damage response-induced checkpoint and repair func...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Shao, Genze, Patterson-Fortin, Jeffrey, Messick, Troy E., Feng, Dan, Shanbhag, Niraj, Wang, Yingqun, Greenberg, Roger A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2009
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661612/
https://ncbi.nlm.nih.gov/pubmed/19261746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1739609
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi