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Species-specific cis-Regulatory Elements in the 3′-Untranslated Region Direct Alternative Polyadenylation of Bone Morphogenetic Protein 2 mRNA

BMP2 (bone morphogenetic protein 2) is a multifunctional member of the transforming growth factor-β family of growth factors. Disruption of BMP2 signaling results in developmental defects, cancers, and other diseases. BMP2 mRNAs are alternatively polyadenylated, resulting in mRNAs with distinct 3′-u...

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Detalhes bibliográficos
Main Authors: Liu, Donglin, Fritz, David T., Rogers, Melissa B., Shatkin, Aaron J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661379/
https://ncbi.nlm.nih.gov/pubmed/18703506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804895200
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