Alternative polyadenylation of MeCP2: Influence of cis-acting elements and trans-acting factors

The human MeCP 2 gene encodes a ubiquitously expressed methyl CpG binding protein. Mutations in this gene cause a neurodevelopmental disorder called Rett Syndrome (RS). Mutations identified in the coding region of MeCP 2 account for approximately 65% of all RS cases. However, 35% of all patients do...

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Bibliografiske detaljer
Main Authors: Newnham, Catherine M., Hall-Pogar, Tyra, Liang, Songchun, Wu, Jing, Tian, Bin, Hu, Jim, Lutz, Carol S.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096559/
https://ncbi.nlm.nih.gov/pubmed/20400852
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