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Bioinformatic identification of candidate cis-regulatory elements involved in human mRNA polyadenylation

Polyadenylation is an essential step for the maturation of almost all cellular mRNAs in eukaryotes. In human cells, most poly(A) sites are flanked by the upstream AAUAAA hexamer or a close variant, and downstream U/GU-rich elements. In yeast and plants, additional cis elements have been found to be...

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Autors principals: HU, JUN, LUTZ, CAROL S., WILUSZ, JEFFREY, TIAN, BIN
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2005 by RNA Society 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370832/
https://ncbi.nlm.nih.gov/pubmed/16131587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2107305
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