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Bioinformatic identification of candidate cis-regulatory elements involved in human mRNA polyadenylation

Polyadenylation is an essential step for the maturation of almost all cellular mRNAs in eukaryotes. In human cells, most poly(A) sites are flanked by the upstream AAUAAA hexamer or a close variant, and downstream U/GU-rich elements. In yeast and plants, additional cis elements have been found to be...

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書誌詳細
主要な著者: HU, JUN, LUTZ, CAROL S., WILUSZ, JEFFREY, TIAN, BIN
フォーマット: Artigo
言語:Inglês
出版事項: Copyright 2005 by RNA Society 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370832/
https://ncbi.nlm.nih.gov/pubmed/16131587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2107305
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