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Systematic Analysis of Cis-Elements in Unstable mRNAs Demonstrates that CUGBP1 Is a Key Regulator of mRNA Decay in Muscle Cells

BACKGROUND: Dramatic changes in gene expression occur in response to extracellular stimuli and during differentiation. Although transcriptional effects are important, alterations in mRNA decay also play a major role in achieving rapid and massive changes in mRNA abundance. Moreover, just as transcri...

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Main Authors: Lee, Jerome E., Lee, Ju Youn, Wilusz, Jeffrey, Tian, Bin, Wilusz, Carol J.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888570/
https://ncbi.nlm.nih.gov/pubmed/20574513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011201
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