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The RNA-binding Protein CUGBP1 Regulates Stability of Tumor Necrosis Factor mRNA in Muscle Cells: IMPLICATIONS FOR MYOTONIC DYSTROPHY

Type I myotonic dystrophy (DM1) is caused by a triplet repeat expansion in the 3′-untranslated region (UTR) of the dystrophia myotonia protein kinase (DMPK) gene. Pathogenesis is closely linked with production of a toxic RNA from the mutant allele, which interferes with function of several RNA-bindi...

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Autors principals: Zhang, Libin, Lee, Jerome E., Wilusz, Jeffrey, Wilusz, Carol J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504872/
https://ncbi.nlm.nih.gov/pubmed/18559347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802803200
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