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Immunoglobulin class switch recombination: study through human natural mutants

Immunoglobulin class switch recombination deficiencies in humans are exquisite models to analyse the mechanisms of class switch recombination (CSR). Besides defects in CD40L/CD40 interaction, others result from an intrinsic B-cell deficiency. The recent elucidation of the molecular basis of some of...

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Detalhes bibliográficos
Autor principal: Durandy, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660924/
https://ncbi.nlm.nih.gov/pubmed/19008192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0210
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